- Hosts: Ed Jones (Owner – Nutrition World) & Clint Powell
- A variety of topics all related to living a healthy life
Presented by: Nutrition World
Broadcasting from the Nooga Dentistry Studio
Production of: Whitfield Media Group
Title: Post-COVID Gut Health and Rethinking Blood Pressure Targets
[0:04:24] – Nutrition World Health Fair & Upcoming Lectures
- Ed announces Nutrition World’s Health Fair on October 24 (described as one of the biggest in the region).
- Emphasis on two “types of people”: learners vs. non‑learners; audience is framed as “learners.”
- Preview of free 30–40 minute lectures during the fair:
- Dave from Tonal Spine – energy systems and spinal health (non-traditional, beyond standard chiropractic).
- Laura Chastain – Optimize You – especially women’s hormones; described as very skilled and experienced.
- Dr. Shalay (Chicago) – integrative healthcare, helping the body heal itself vs. “band-aid” approaches.
- Charles – Scenic City Neurotherapy – IV ketamine for:
- Chronic anxiety and depression
- PTSD
- Some applications in joint pain/arthritis (Ed notes his own experience for hip pain).
- Strong emphasis on root-cause medicine vs. symptom masking.
[0:08:25] – Butter Wrappers & “Forever Chemicals”
- Ed raises a niche but practical topic: chemicals in butter wrappers.
- Refers to testing reported by Mammovation:
- Higher concern (more fluorine / “forever chemicals”):
- Kerrygold Pure Irish Butter
- Land O’ Lakes salted butter
- Better / lower concern options:
- Kirkland (Costco) – lower levels
- Best butter wrappers listed:
- Whole Foods Market butter
- Horizon
- Kate’s Salted
- Kirkland Organic Salted Butter
- Higher concern (more fluorine / “forever chemicals”):
- Takeaway: Shop with knowledge; packaging/liners can be a hidden health variable.
[0:12:50] – Nurse Practitioner Meredith Mason (Brio Functional Medicine)
- Introduction:
- Guest: Meredith Mason, NP, founder of Brio Functional Medicine (opened in 2018).
- Ed recalls having her on roughly seven years ago.
- COVID & long-COVID context:
- Meredith had two years of practice before COVID; she values that pre-COVID baseline.
- Notes a “triad” she sees repeatedly since COVID:
- Chronic fatigue
- Mast cell / high-histamine symptoms
- Digestive complaints / gut issues
- Clinic intake includes a 20-page questionnaire; many patients answer “When did you last feel well?” with:
- “2019”
- “Before I had COVID”
- “Before COVID vaccination”
- Meredith’s personal health journey:
- At ~18–19, she had a mysterious illness with severe throat infection, ER visit, fatigue, and eventual chronic pain and fatigue.
- This pushed her toward integrative and root-cause medicine.
- COVID leading to apparent Epstein–Barr reactivation:
- After an infection in late 2021, she develops:
- Marked fatigue
- Mast-cell-type histamine issues
- Digestive symptoms
- Suspects Epstein–Barr virus (EBV) reactivation, not just mitochondrial dysfunction.
- Meredith’s own approach:
- Used a Kasia Kines‑style nutritional protocol plus antivirals with a Florida physician.
- Her Early Antigen D normalized, with improved fatigue.
- After an infection in late 2021, she develops:
- EBV & herpesvirus family:
- Clarifies: Epstein–Barr is a herpesvirus, in the same family as:
- CMV (cytomegalovirus)
- HSV-1/HSV-2
- Varicella (chickenpox)
- High-dose lysine known to slow replication of herpes viruses.
- Clarifies: Epstein–Barr is a herpesvirus, in the same family as:
[0:23:14] – H. pylori, Histamine Intolerance & Post-COVID Gut Changes
- Meredith’s own mast-cell / histamine journey:
- Developed severe histamine symptoms post-COVID.
- Conventional H1 and H2 blockers (Claritin, Zyrtec, Pepcid/Famotidine) did not resolve issues.
- She also tried quercetin, luteolin, and evaluated genetics (DAO and HNMT) but didn’t find a complete explanation.
- Turning to the gut:
- Ordered a GI-MAP functional stool test and found:
- Citrobacter freundii and Klebsiella pneumoniae – both high histamine‑producing bacteria.
- Hypothesis:
- COVID changes the gut microbiome (e.g., lowering beneficial Bifidobacteria), creating an environment for histamine‑producing species to overgrow.
- Ordered a GI-MAP functional stool test and found:
- Widespread H. pylori findings:
- In recent stool tests, >90% of her patients are now positive for H. pylori.
- H. pylori:
- Is a mast-cell activator
- Classically associated with stomach ulcers, but also with pancreatic cancer
- Meredith notes a personal family loss to pancreatic cancer in someone with prior H. pylori.
- Testing approaches:
- Functional medicine: GI-MAP (DNA-based) often picks up H. pylori even when:
- Breath tests,
- Endoscopic biopsies, or
- Traditional antibody tests
come back negative.
- Distinguishes:
- Blood antibodies – tell you if you’ve ever had H. pylori, not necessarily current infection.
- Stool antigen/DNA – better for current infection.
- Functional medicine: GI-MAP (DNA-based) often picks up H. pylori even when:
- When to treat:
- She monitors elastase-1 (pancreatic enzyme output) on stool testing:
- Low elastase suggests H. pylori may be impairing stomach acid and downstream digestion.
- She monitors elastase-1 (pancreatic enzyme output) on stool testing:
- Treatment approach:
- Main tool: Mastic gum (a Mediterranean shrub extract) twice daily.
- Sometimes bismuth/Pepto‑style support depending on symptoms.
- Ed notes he often feels better whenever he uses mastic gum and now wants to test himself for H. pylori.
- Secretory IgA & post-COVID gut immunity:
- She’s seeing dramatic reductions in secretory IgA (sIgA) on stool results—even in people in their 20s.
- sIgA = the primary immune antibody at the gut lining.
- Her working view:
- COVID appears to suppress gut immune function, making people more vulnerable to pathogens like H. pylori and histamine-producing bacteria.
- Core goal at Brio: heal leaky gut, rebuild sIgA, and restore gut-driven immunity.
- Clinic details:
- Brio Functional Medicine (Lee Highway “wellness corner” next to Nutrition World).
- Offers in‑person and telemedicine consultations.
- Contact: briomedicine.com and info@briomedicine.com.
[0:35:42] – Dr. Curt Dearing on Blood Pressure & Conventional Medicine
Historical BP Targets & Over-Lowering Risks
- Dr. Curt Dearing outlines four major issues with conventional blood pressure management.
- Evolving guidelines:
- 1977 Joint National Committee (JNC):
- Acceptable up to 160/95; treatment mainly when diastolic ≥105.
- JNC 5 and 7: 140/90 becomes standard; 130/80 suggested for high-risk (diabetes, CKD).
- 2017 ACC/AHA: 130/80 becomes diagnostic threshold.
- Some now push for “optimal” ~110/70.
- 1977 Joint National Committee (JNC):
- Curt’s view:
- For older adults, the vascular system changes; some rise in BP is normal and necessary.
- Aggressively pushing older patients into 110s/60s can be harmful.
- J-curve phenomenon:
- As BP is lowered, risk decreases until a threshold, after which lower BP increases risk again.
- Key data he cites:
- 2018 Lancet (1+ million patients):
- No increased mortality at 150/100.
- American Journal of Hypertension:
- All-cause mortality increases at ~110/70 range.
- 2018 Lancet (1+ million patients):
- Practical implication:
- Very low BP (especially diastolic <70) can reduce blood flow to the:
- Brain
- Heart
- Kidneys
- In older adults, overly low BP is linked with falls, fractures, strokes, cognitive decline, and kidney damage.
- He references a nursing home study where reducing blood pressure meds led to fewer fractures, strokes, heart attacks, and deaths.
- Very low BP (especially diastolic <70) can reduce blood flow to the:
[0:41:06]– When Medication Makes Sense & Root-Cause Thinking
- Curt emphasizes BP is a symptom, not the disease:
- Common drivers:
- Inflammation
- Insulin resistance
- Sedentary lifestyle
- High stress
- Mitochondrial dysfunction
- Common drivers:
- Reasonable thresholds (his philosophy):
- Cites Dr. David Brownstein’s rule of thumb:
- “90 + your age” for systolic as a tolerable upper range, with common sense caveats.
- Example: age 60 → occasionally up to 150 systolic can be acceptable.
- He becomes more concerned if numbers are persistently:
- Systolic near 170
- Diastolic consistently >100
and root causes can’t be corrected quickly.
- In those cases, he supports using medication as a temporary band‑aid while working on underlying causes.
- Cites Dr. David Brownstein’s rule of thumb:
- Risks of certain meds:
- Example: Amlodipine (calcium channel blocker):
- Excellent at lowering BP numbers.
- But may promote calcium deposition in arteries, potentially increasing cardiovascular disease over time.
- Example: Amlodipine (calcium channel blocker):
[0:44:53] – Salt Intake, DASH Diet & Heat Risk
- Conventional advice: “Lower salt to lower blood pressure.”
- Curt’s critique:
- DASH diet improved BP, but it involved many variables:
- Reduced refined carbs
- Better overall diet quality
- He argues improved insulin sensitivity and lower inflammation, not sodium restriction alone, drove most benefits.
- Pure sodium-reduction-only studies typically show:
- BP improvements of only 1–2 mmHg.
- DASH diet improved BP, but it involved many variables:
- Downsides of excessive sodium restriction:
- Can worsen insulin resistance – the opposite of what hypertensive patients need.
- In the context of heat:
- Low salt intake raises risk for heat-related illness and heat stroke.
- Historical example: 1995 Chicago heat wave – many elderly were salt-restricted.
- EMS/ER standard: in heat stroke, one of the first interventions is IV sodium chloride.
- Balanced message:
- Overdoing salt in single meals can acutely spike BP, but adequate daily sodium, especially in hot weather and with sweating, supports:
- Blood volume
- Perfusion
- Safer cardiovascular function
- Prefers minimally processed, mineral-rich salts (e.g., certain tested Himalayan salts) over refined table salt.
- Overdoing salt in single meals can acutely spike BP, but adequate daily sodium, especially in hot weather and with sweating, supports:
[0:48:50] – Lifestyle & Nutraceutical Support for Blood Pressure
- Curt notes:
- 2020 Journal of Human Hypertension: lifestyle changes alone can lower BP up to 15 mmHg.
- Emphasizes:
- Diet and carb quality
- Regular movement
- Stress reduction
- Also highlights evidence-supported supplements:
- Magnesium
- Omega‑3 fatty acids
- CoQ10
- Others available through Nutrition World.
[0:54:14] – Protein & Kidney Function
- Ed shares a study on protein intake and kidney function:
- Using eGFR (estimated glomerular filtration rate) over 10 years in 13,124 adults (avg age 64).
- Finding: higher protein intake was not associated with declining kidney function, even in:
- Diabetes
- Hypertension
- Higher albumin levels.
- Another study in ~8,500 adults:
- Higher protein intake was associated with a slightly lower risk of mortality vs. low protein.
- Takeaway:
- For most people (including those at some CKD risk), adequate or higher protein does not automatically “wreck kidneys.”
- Ed reinforces that muscle is the “organ of longevity”, so protein should not be casually restricted out of fear.
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